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Yingtian Pan, Ph.D.
Assistant Professor of Biomedical Engineering.
Funding through National Institute of Diabetes and Digestive and Kidney
Diseases and the Whitaker Foundation.
Figure 1. In vivo 3D OCT of living
human skin (a scar). Image size (mm): x/3.6, y/2, z/2. Arrows:
a sweat duct, dashed circles: the area of epidermal and dermal
granulation of scar with increased scattering. |
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Research in my lab is focused on noninvasive and high resolution optical
imaging diagnosis of biological tissue. 2-D and 3-D cross-sectional optical
imaging of biological tissue at close to cellular resolution (e.g., 10um)
and at depths of 1-3mm can have significant impacts on noninvasive or
minimally invasive clinical diagnosis of tissue abnormalities (e.g., tumorigenesis)
and engineering tissue growth and repair. Core technological developments
in my lab include MEMS-based laser scanning endoscopy and fluorescence
microscopy, with the ultimate goal of developing optical biopsy or optically
guided biopsy to assist early epithelial cancer diagnosis and engineering
tissue growth in the clinical environment. Encouraging results based on
animal and human studies show that laser scanning endoscopy can be integrated
with conventional endoscopy to provide morphological details correlated
well with excisional histology, suggesting its potential for optical biopsy
or optically guided biopsy to reduce negative biopsies in clinical practice.
Current applications of my lab are focused on early-stage epithelial cancer
detection, diagnosis of cartilage injury and repair, and assessment of
engineering tissue growth in joint tissue and skin. In addition, my lab
studies skin dehydration, geriatric incontinence and laser/biochemical
attack to the eye using optical coherence tomography, fluorescence imaging
and light microscopy.
The biomedical oriented students will be encouraged to apply the imaging
technique to animal and human specimens to study clinical problems such
as cancers and engineering tissue growth. She/he will work on independent
project which includes imaging specimens, documenting results and comparing
them with histological evaluations. The engineering oriented students
will be exposed to state-of-the-art bioimaging techniques and will be
encouraged to develop interesting electrical/mechanical/optical subsystems
for different imaging applications. Students will discuss scientific progress
and technical challenges at weekly lab meetings to promote cooperative
learning and team work.
Contact Information
email: Yingtian.Pan@sunysb.edu
url: http://www.bme.sunysb.edu/bme/people/faculty/y_pan.html
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