A unique electrospinning technique
to produce bioabsorbable polymer membranes (polylactide (PLA), polyglycolide
(PGA) and copolymers) has been developed in Chu/Hsiao laboratory
in Department of Chemistry at Stony Brook. The membranes are designed
for uses in prevention of post-operative adhesions, which overcome
several problems in commercial products. The goal of this proposal
is to request the funding for a Phase I Seed Grant to initiate an
in-vivo study of the membrane (by Brathwaite) in the Department
of Surgery at the University Hospital and Medical Center in order
to commercialize these novel materials. The detailed animal testing
protocol and animal use plans are outlined in this proposal. If
successful, many aspects of this technology (material compositions,
fabrication techriiques, procedures and applications) can be patented.
A preliminary economic evaluation indicates that the potential financial
return based on this technology is quite substantial and will be
of major benefit to New York State. |
